RadEssentialReading-room reference

PI-RADS v2.1

v2.1 2019MRIProstate

Dominant sequence: DWI for peripheral zone, T2W for transition zone. DCE only upgrades PZ score 3 to 4. Size cutoff for 4 vs 5 is 1.5 cm.

PZ · DWI score

ScoreFinding
1Normal on ADC and high b-value
2Linear or wedge-shaped hypointense on ADC and/or hyperintense on high b
3Focal, mildly/moderately hypointense on ADC and/or iso/mildly hyperintense on high b; may be markedly abnormal on one but not both
4Focal markedly hypointense on ADC and markedly hyperintense on high b; <1.5 cm
5As 4 but ≥1.5 cm, or definite extraprostatic extension/invasive behavior

TZ · T2W score

ScoreFinding
1Normal TZ, or round completely encapsulated nodule (typical nodule)
2Mostly encapsulated nodule, or homogeneous circumscribed nodule without encapsulation (atypical nodule), or homogeneous mildly hypointense area between nodules
3Heterogeneous signal with obscured margins; anything not fitting 2, 4 or 5
4Lenticular or non-circumscribed, homogeneous, moderately hypointense; <1.5 cm
5As 4 but ≥1.5 cm, or definite extraprostatic extension/invasive behavior
Overall category
PI-RADS–
PZ: DWI 3 + DCE positive → 4. TZ: T2W 2 + DWI ≥4 → 3; T2W 3 + DWI 5 → 4. DCE positive = focal early enhancement corresponding to a T2W/DWI finding.

Sources

  1. Turkbey B, Rosenkrantz AB, Haider MA, et al. Prostate Imaging Reporting and Data System version 2.1: 2019 update of Prostate Imaging Reporting and Data System version 2. Eur Urol. 2019;76:340–351.PubMed ↗

Radessential summarizes published classification systems for practicing radiologists. Summaries are condensed; confirm details against the cited source before relying on them for patient care.