RadEssentialReading-room reference

CAD-RADS 2.0

SCCT/ACR/NASCI 2022CTACardiac
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Stenosis categories and stable chest pain management
Plaque burden, modifiers and high-risk plaque features

Report the highest-grade stenosis in any vessel over 1.5 mm, then plaque burden, then modifiers, e.g. CAD-RADS 3/P2/HRP/I+. Version 2.0 added plaque burden (P1–P4) and ischemia (I), and replaced the old V modifier with HRP.

Stenosis category

CategoryStenosisStable chest pain: next step
00%, no plaqueNo further cardiac testing
11–24%, or plaque with positive remodeling but no stenosisPreventive therapy
225–49%Preventive therapy
350–69%Consider functional testing
4A70–99% in 1 or 2 vesselsICA or functional assessment
4BLeft main ≥50%, or 3-vessel ≥70%Invasive angiography
5100% (total occlusion)ICA and/or viability
NNon-diagnostic studyAdditional evaluation

Plaque burden

GradeDescriptorCAC scoreSegment involvement score
P1Mild1–1001–2
P2Moderate101–3003–4
P3Severe301–9995–7
P4Extensive≥1000≥8

Modifiers

ModifierMeaning
NOne or more non-diagnostic segments; if a diagnostic segment shows ≥50%, report 3/N rather than N alone
HRPHigh-risk plaque: 2 or more of low attenuation (<30 HU), positive remodeling, spotty calcification, napkin-ring sign
I+ / I− / I±Ischemia from CT-FFR or stress CT perfusion: present, absent, or indeterminate
SStent present
GBypass graft present; bypassed native stenoses are not graded
EException: non-atherosclerotic cause such as anomalous origin, dissection, aneurysm, vasculitis, fistula or extrinsic compression
Acute chest pain uses different management recommendations, e.g. CAD-RADS 3 warrants functional testing or admission depending on troponin and HRP. Check the consensus tables before applying in the emergency setting.

Sources

  1. Cury RC, Leipsic J, Abbara S, et al. CAD-RADS™ 2.0 – 2022 Coronary Artery Disease-Reporting and Data System: an expert consensus document of the Society of Cardiovascular Computed Tomography (SCCT), the American College of Radiology (ACR) and the North American Society for Cardiovascular Imaging (NASCI). J Cardiovasc Comput Tomogr. 2022;16:536–557.PubMed ↗

Radessential summarizes published classification systems for practicing radiologists. Summaries are condensed; confirm details against the cited source before relying on them for patient care.